Climate Chamber ICH

Climate chamber

Climate chamber for stability testing in accordance with ICH – WHO – EMA – ASEAN – GMP – GLP – GCCP.

Intuitive Operation
Touch, turn & go! Easy and intuitive operation with the unique Memmert ControlCOCKPIT and software AtmoCONTROL.

Unlimited communication
Memmert appliances are equipped with state of the art interfaces for programming and communication.

Safety
Safety of users and chamber loads: electronic temperature monitoring system, mechanical temperature limiter as well as an integrated auto-diagnostic system.

Climate chamber ICH for stability testing in accordance with ICH and GMP

Its excellent temperature and humidity homogeneity positions the climate chamber ICH in the international top league of stability test chambers. Thermal transfer to the interior – whether heat or cold – is guaranteed through a large-area air jacket on four sides. Thanks to its hermetically sealed interior, the climate chamber ICH does not consume any water once the setpoints have been reached, provided that the door is not opened. Two high-grade platinum temperature sensors with mutual monitoring guarantee interruption-free long-term operation even if one sensor should fail.

  • Digitally controlled active humidification and dehumidification from 10 to 80 % rh
  • Temperature range from – 10 °C to + 60 °C (models ICH), 0 °C to + 60 °C (modelsICHL)
  • 1 model variant – TwinDISPLAY
  • double doors as standard: Prevention of contamination and drops or prevention of rises in temperature with an optimal view of the chamber load through wide-area interior glass doors

ICH stability testing (Q1B, option 2) in the climate chamber ICHL

In the climate chamber ICHL, a lighting unit can be used for testing in accordance with the ICH guidelines Q1B, option 2 (photostability). Fluorescent lamps with cold white light (daylight: light color 865, 6,500 K) and UV radiation in the spectral range 320 – 400 nm serve as the light source. Daylight and UV light correspond to standard light D65.

Temperature-humidity working range ICH

Not all climate chambers are the same. The humidity content of the chamber load, the ambient conditions and the respective temperature-humidity working range are decisive factors in the selection of the right appliance. In the adjacent diagram, you can see the possible temperature/humidity combinations for our climate chamber ICH.

Within the respective temperature-humidity range, condensation-free permanent operation is possible. To which extent condensation may occur in the threshold range depends on the humidity content of the chamber load and the ambient conditions.

If this does not match your temperature-humidity working range, see the other Memmert climate chambers we supply:

See all our Memmert heating cabinets and incubators.

Download the climate chamber ICH brochure.

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Order information about Climate chambers
Order information about Climate chambers

Climatic chambers

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Memmert Klimakammer ICH750L

Climate chamber ICH750L

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Memmert Klimakammer ICH260L

Climate chamber ICH260L

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Memmert Klimakammer ICH110L

Climate chamber ICH110L

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Contact us

Frode Rangset

Frode Rangset

+47 948 26 016
frode@labhuset.no

We would like to hear from you if you have any questions or inquiries about our services and products!

Get an offer

Send melding - Frode (Engelsk)

Contact us

Frode Rangset

We would like to hear from you if you have any questions or inquiries about our services and products!

Frode Rangset

+47 948 26 016
frode@labhuset.no

Product Specifications

Areas of Use

The Memmert ICHL climate chamber is built specifically for stability testing of pharmaceuticals and biological preparations to international guidelines — including photostability testing with the integrated light module. Typical applications include:

  • Stability testing of pharmaceuticals to ICH Q1A, Q1B and Q1C
  • Photostability testing to ICH Q1B option 2 with cold white light and UV radiation
  • Long-term stability testing at 25 °C / 60 % rh and 30 °C / 65 % rh
  • Accelerated stability testing at 40 °C / 75 % rh
  • Climate testing to WHO, EMA, ASEAN and GCCP guidelines
  • GMP/GLP-validated stability testing with full documentation (IQ/OQ/PQ)
  • Storage and testing of biological samples, vaccines and diagnostics
  • Exposing pharmaceuticals to light under controlled climatic conditions

Advantages

Temperature and humidity homogeneity in the top class
The large air jacket on four sides distributes heat and cold evenly throughout the chamber. On temperature and humidity homogeneity, the ICH sits among the leading stability test chambers internationally.

Integrated light module for photostability testing — ICH Q1B option 2
The light module carries cold white light (daylight: light colour 865, 6,500 K) and UV lamps (320–400 nm) matching standard illuminant D65. Both light types are controlled separately from the controller, which is what makes documented photostability testing of pharmaceuticals practical.

Hermetically sealed chamber — no water evaporation
The sealed interior means the chamber consumes no water once setpoints are reached, provided the door stays shut. That cuts running costs and the need for refilling substantially.

Redundant platinum sensors
Two Pt100 sensors (DIN Class A, 4-wire) with mutual monitoring keep operation running even if one sensor fails. That matters in long-term stability studies where an interruption invalidates the run.

Digitally controlled active humidification and dehumidification
Precise digital humidity control from 10 to 80 % rh, with setting accuracy of 0.5 %, regulating actively in both directions. This makes reproducible testing possible across the standard ICH climate zones.

No drying-out of the load
The thermal jacket is separated from the interior, so the cooling system cannot dry out the chamber load — a common weakness in chambers where the evaporator sits in the working space.

GMP/GLP validation and documentation
Full IQ/OQ/PQ documentation available. FDA-compliant AtmoCONTROL (21 CFR Part 11). DAkkS calibration to DKD-R 5-7 as an option.

TwinDISPLAY and AtmoCONTROL
ControlCOCKPIT operation via TFT touchscreen. Full programme control, USB connectivity and Ethernet communication through AtmoCONTROL. Programmes are retained through a power failure.

Technical specifications

Read more in the Memmert climate chamber brochure.

Functions

  • Air jacket on four sides for highly homogeneous temperature and humidity distribution
  • Thermal jacket separated from the interior — the cooling system cannot dry out the load
  • Hermetically sealed chamber — minimal water consumption at stable setpoints
  • Two redundant Pt100 platinum sensors (DIN Class A, 4-wire) with mutual monitoring
  • Digitally controlled active humidification and dehumidification (10–80 % rh, accuracy 0.5 %)
  • Humidification by hot steam generator, fed from an external tank by self-priming pump
  • Light module for ICH Q1B option 2: cold white lamps plus 2 UV lamps, separately controllable
  • Forced air circulation adjustable from 10 to 100 % in 10 % steps
  • Highly efficient automatic defrosting system
  • CFC-free cooling and heating system (refrigerant R134a)
  • Double doors as standard — insulated stainless steel outside, glass inside
  • Mechanical temperature limiter TB (protection class 1, DIN 12880)
  • Over- and undertemperature monitor TWW (class 3.3) or adjustable limiter TWB (class 2), selectable on the display
  • AutoSAFETY (ASF) — automatic over- and undertemperature protection
  • Autodiagnostic system for temperature and humidity control
  • SetpointWAIT — process time only starts once the set temperature is reached
  • Digital timer: 1 minute to 99 days
  • TwinDISPLAY (TFT touchscreen) with ControlCOCKPIT operation
  • AtmoCONTROL software for programming and communication via USB or Ethernet
  • Silicone entry port, 40 mm clear diameter, moisture-tight, rear wall as standard
  • Water tank with connection hose included
  • 2 electropolished stainless steel grids included
  • All models on lockable castors
  • Compressed-air dehumidification (option C9) for efficient dehumidification down to 10 % rh
  • Door with lock and key (option B6)
  • MobileALERT SMS notification on alarm (option C3)
  • FDA-compliant AtmoCONTROL (option FDAQ1)
  • IQ/OQ/PQ documentation available
  • DAkkS calibration available (options E48847/E48848)
  • Compliance: DIN 12880:2007-05, EN 61010-1, EN 61010-2-010

Model overview

Documentation

Individual datasheets are available for all models:

Download the shared climate chamber ICH brochure here.

Key technical data:

  • Setting temperature range: 0 °C to +60 °C
  • Working range with humidity and/or light: +10 °C to +60 °C
  • Setting accuracy, temperature: 0.1 °C
  • Humidity: 10–80 % rh, setting accuracy 0.5 %
  • Volume: 108–749 litres (3 sizes)
  • Display: TwinDISPLAY (all models)
  • Standard calibration: +10 °C and +37 °C, 60 % rh at +30 °C
  • Power supply: 230 V or 115 V, 50/60 Hz
  • Ambient conditions: 15 °C to 28 °C, max. 70 % rh non-condensing
  • Compliance: DIN 12880, EN 61010-1, EN 61010-2-010

Who is the Memmert Climate chamber ICH for?

The Memmert ICHL suits organisations and laboratories that need documented stability testing under controlled climatic and lighting conditions. It is a particularly good fit for:

  • Pharmaceutical manufacturers and R&D laboratories working to ICH Q1A, Q1B and Q1C
  • Contract laboratories running photostability testing on behalf of drug manufacturers
  • Regulatory laboratories with GMP, GLP and GCCP compliance requirements
  • Universities and research institutes running climate-controlled long-term studies
  • Diagnostics and vaccine manufacturers with WHO and EMA compliance requirements
  • Laboratories needing combined climate and light control in a single instrument

Note: if your temperature-humidity working range falls outside the ICH series, see the Memmert constant climate chamber HPPeco or the humidity chamber HCP.

About the Manufacturer – Memmert GmbH

Memmert is a German manufacturer with more than 90 years of experience in laboratory ovens, incubators and climate chambers. Founded in Schwabach, Bavaria in 1933, the family-owned company is today one of the world’s leading suppliers of temperature-controlled laboratory equipment.

  • Founded: 1933
  • Address: Äußere Rittersbacher Str. 38, 91126 Schwabach, Germany
  • Website: www.memmert.com
  • Specialities: heating ovens, incubators, climate chambers, vacuum ovens and water baths
  • Quality: ISO 9001-certified manufacturing

Memmert products are used worldwide in research, pharmaceuticals, food production, electronics and industry. Industrihuset carries the full Memmert range, adapted to Norwegian laboratories and businesses.

Order information about Climate chambers
Order information about Climate chambers

FAQ

Frequently Asked Questions

The ICH (International Council for Harmonisation) defines standardised climatic conditions for stability testing of pharmaceuticals. The most common are long-term at 25 °C / 60 % rh (zone II), intermediate at 30 °C / 65 % rh (zones III/IV) and accelerated at 40 °C / 75 % rh (zone IVb). The Memmert ICHL supports all of these within its working range.

ICH Q1B sets out the requirements for exposing pharmaceuticals to light to document photostability. Option 2 uses a combined light source of cold white daylight (D65, 6,500 K) and UV radiation (320–400 nm). The Memmert ICHL carries exactly that combination, and both light types are controlled separately from the controller.

The hermetically sealed interior stops humid air escaping. The moisture circulates internally with no loss to the surroundings, which cuts the need for refilling substantially during long test runs — a practical and financial advantage over the length of a stability study.

Yes, and it is worth planning for. Without humidity the setting range is 0 °C to +60 °C. With humidity and/or the light module in use, the working range starts at +10 °C. All standard ICH climate zones sit comfortably inside that, but it rules out sub-10 °C testing with humidity control.

Yes. Options ZWVR6 (with filter cartridges) and ZWVR7 (without, for demineralised water at 5–10 µS/cm conductivity) allow the chamber to be plumbed into the building water supply, removing the need to refill the tank by hand.

Yes. Industrihuset is the authorised Norwegian distributor for Memmert. We provide consultation, installation, calibration and support with IQ/OQ/PQ documentation. Contact frode@labhuset.no or call +47 948 26 016.

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